Transient receptor potential cation channels in disease.
By B. Nilius, G. Owsianik, T. Voets, John A. Peters. Physiological Reviews, 2007
1,420 citations recorded by the source corpus.
Subfields: Nutrition and Dietetics, Physiology, Sensory Systems
View Paper: https://www.semanticscholar.org/paper/3ef62f161b28e02dd7a4abb64856c063008aece3
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In Nutrition and Dietetics
In Physiology
In Sensory Systems
Citations in the corpus
- Central mechanisms of osmosensation and systemic osmoregulation (2008, background): “that osm-9 , a gene that is mutated in a mutant line of Caenorhabditis elegans that lacks an avoidance response to strongly hyperosmolar solutions, encoded a member of the superfamily of transient receptor potential (TRP) channel”
- Direct binding of α‐actinin enhances TRPP3 channel activity (2007, background): “It is classified as a member of the TRP superfamily of cation channels (Clapham 2003; Ramsey et al. 2006; Nilius et al. 2007).”
- PI(3,5)P2 Controls Membrane Traffic by Direct Activation of Mucolipin Ca2+ Release Channels in the Endolysosome (2010, background): “Mutations in the human TRPML1 gene cause mucolipidosis type IV (ML4) neurodegenerative diseas”
- TRP Channels (2012, neutral): “constitutively activated channel, whose activity can be further enhanced by stimulation of G protein-coupled receptor or DAG 2 + Pore properties TRPC7, like TRPC6, exhibits P Ca2 + /P Na + of 0.5 (315,375).”
- The transient receptor potential family of ion channels (2011, background): “TRPs and disease Several TRP genes are implicated in a wide range of diseases in humans [30,31].”
- Physiological implications of hydrogen sulfide: a whiff exploration that blossomed. (2012, background): “They are TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPP (polycystin), TRPML (mucolipin), and TRPA (ankyrin) (440).”
- SOAR and the polybasic STIM1 domains gate and regulate the Orai channels (2009, background): “TRPC channels function as non-selective, Ca 2+ -permeable channel”
- International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2 (2010, background): “It is noteworthy that mutations in different TRPs have been linked to human diseases, and their expression in tissues affected by pathological conditions is often increased (Nilius et al., 2007).”