Exposure to Carbon Nanotube Material: Assessment of Nanotube Cytotoxicity using Human Keratinocyte Cells

By A. Shvedova, Vincent Castranova, E. Kisin, D. Schwegler-Berry, A. Murray, V. Z. Gandelsman, Andrew D. Maynard, P. Baron. Journal of Toxicology and Environmental Health, Part A, 2003

1,222 citations recorded by the source corpus.

Subfields: Cancer Research, Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/3e155d86c3a627a95028cc802398d71f192f51a7

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In Materials Chemistry

1. Kostas Kostarelos
2. M. Prato
3. A. Bianco
4. R. Handy
5. C. Partidos
6. J. Rhim
7. G. Oberdörster
8. W. D. De Jong

Citations in the corpus

• Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy (2005, background): “Dosing keratinocytes and bronchial epithelial cells in vitro with SWCNT has been shown to result in increases in markers of oxidative stress [50,53,54].”
• Exposure to Carbon Nanotube Material: Aerosol Release During the Handling of Unrefined Single-Walled Carbon Nanotube Material (2004, background): “In a companion article, data are presented on human keratinocyte cell response to unrefined SWCNT material (Shvedova et al., 2003).”
• Multi-walled carbon nanotube interactions with human epidermal keratinocytes. (2005, background): “Evidence of dermal irritati Eedy, 1996) coupled with a report of toxicity to ke tinocytes (Shvedova et al., 2003) suggests that par les not optimized for intracellular delivery may en ells and adversely affect cellular function.”
• Nanotechnology and Water Treatment: Applications and Emerging Opportunities (2008, background): “…et al. 2002; Chen et al. 2004; Maynard and Kuempel 2005; Oberdörster et al. 2005; Donaldson et al. 2006; Lam et al. 2006), chemical composition (Shvedova et al. 2003; Donaldson et al. 2006), as well as surface treatments (coatings) and the degree to which nanoparticles aggregate or…”
• Better safe than sorry: Understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications. (2010, background): “[12] reported that the addition of a metal chelator reduced the cytotoxicity”
• Metal Oxide Nanoparticles Induce Minimal Phenotypic Changes in a Model Colon Gut Microbiota (2015, neutral): “Multiple changes in eukaryotic cellular morphology, which include changes in cell size such as cell rounding, nuclear membrane blebbing, chromatin condensation, and alterations in cytoplasmic organelles, have been associated with cytotoxicity caused by quantum dots and single-walled carbon nanotubes”
• Mechanisms of Nanoparticle-Induced Oxidative Stress and Toxicity (2013, background): “SWCNT with 30% iron by mass Lipid peroxidation, reduced cell viability, and antioxidant reserve in human keratinocytes [170]”
• Effect of single wall carbon nanotubes on human HEK293 cells. (2005, background): “Carbon nanotubes exhibit cytotoxicity to human keratinocyte cells (Robert, 2003; Shvedova et al., 2003), can inhibit the growth of embryonic rat-brain neuron cells (Mattson et al.”
• Transport of engineered nanoparticles in saturated porous media (2010, background): “Recent studies of environmental impacts of CNTs, however, have generally shown toxic effects of CNTs toward the ecosystem, particularly with respect to aquatic organisms (Bottini et al. 2006; Kennedy et al. 2008; Manna et al. 2005; Roberts et al. 2007; Shvedova et al. 2003; Warheit et al. 2004).”