Insulin and insulin resistance.

By G. Wilcox. Clinical biochemist reviews, 2005

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Pathophysiology of Type 2 Diabetes Mellitus (2020, background): “Hence, excessive secretion of these hormones may be responsible for inducing IR [155,156].”
Trends in insulin resistance: insights into mechanisms and therapeutic strategy (2022, background): “As mentioned above, the primary characteristics of IR are inhibited lipolysis in adipose tissue, impaired glucose uptake by muscle and inhibited gluconeogenesis in liver.(305) Nevertheless, IR can be linked to a cluster of abnormal syndrome (Fig.”
Association between insulin resistance and the development of cardiovascular disease (2018, background): “During insulin resistance and/or hyperinsulinemia, normal glucose tolerance is maintained due a series of physiological changes activated by these phenomenon [5].”
Flavonoids and Their Anti-Diabetic Effects: Cellular Mechanisms and Effects to Improve Blood Sugar Levels (2019, background): “Insulin resistance is defined as an impaired sensitivity to insulin due to an increase insulin secretion [16].”