Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection.

By R. Greif, O. Akça, E. Horn, Andrea Kurz, Daniel I. Sessler. New England Journal of Medicine, 2000

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Major congenital malformations after first-trimester exposure to ACE inhibitors. (2006, background): “Increasing oxygen concentration has been linked to improved wound healing.(2) Five hundred patients undergoing colorectal surgery were randomized to a high or low oxygen concentration group.”
Wound Microbiology and Associated Approaches to Wound Management (2001, background): “Elevation of the oxygen tension in perfused tissue during colorectal surgery by the administration of 80% inspired oxygen has been shown to significantly reduce the incidence of postoperative wound infection (91).”
Multimodal strategies to improve surgical outcome. (2002, background): “However, early postoperative oxygen administration may reduce nausea and vomiting [83] decrease the incidence of surgical wound infection [109], and reduce tachycardia [110].”