Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes
By J. Gudmundsson, P. Sulem, V. Steinthorsdottir, J. Bergthórsson, G. Thorleifsson, A. Manolescu, T. Rafnar, Daniel Fannar Gudbjartsson, B. Agnarsson, A. Baker and 65 more. Nature Genetics, 2007
755 citations recorded by the source corpus.
Subfields: Genetics, Molecular Biology, Pulmonary and Respiratory Medicine
View Paper: https://www.semanticscholar.org/paper/3c1a57215b13aa4ba39879c8be0207aa65372774
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In Genetics
- Gonçalo R. Abecasis
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- Yun Li
- Mark J. Daly
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In Molecular Biology
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Citations in the corpus
- SNPFile – A software library and file format for large scale association mapping and population genetics studies (2008, neutral): “Background High-throughput genotyping technology has enabled cost effective typing of thousands of individuals in hundred of thousands of markers for use in genome wide studies [1], in particular genome disease association studies [2-7].”
- Consistent Association of Type 2 Diabetes Risk Variants Found in Europeans in Diverse Racial and Ethnic Groups (2010, background): “With the exception of the KCNQ1 locus which was identified in the Japanese population [1,2], all of the well-replicated risk variants were first identified in populations of Northern European ancestry [3–13].”
- STrengthening the REporting of Genetic Association Studies (STREGA)— An Extension of the STROBE Statement (2009, neutral): “org 0158 February 2009 | Volume 6 | Issue 2 | e1000022 association studies [85,87–105].”
- Multiple loci identified in a genome-wide association study of prostate cancer (2008, background): “, two of which have been replicated by independent groups, and in HNF1B (formerly TCF2”
- Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21 (2011, neutral): “ETO, a target of t(8;21) in acute leukemia, makes distinct”