Lysosomal cysteine proteases: more than scavengers.
By B. Turk, D. Turk, V. Turk. Biochimica et Biophysica Acta, 2000
813 citations recorded by the source corpus.
Subfields: Cancer Research, Cell Biology, Physiology
View Paper: https://www.semanticscholar.org/paper/3bfa11e0ab5002c35c514cfa76ed8ac79d46c409
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In Cancer Research
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Citations in the corpus
- Cysteine cathepsins: From structure, function and regulation to new frontiers (2011, background): “degrade intracellular and extracellular proteins [17,21].”
- The autophagosomal–lysosomal compartment in programmed cell death (2001, background): “Other lysosomal cysteine proteases such as cathepsin B,C,L have been implicated in caspase activation as well.(97,102,103) In particular, in cell free systems purified cathepsin B has been found to directly cleave caspase zymogens: it readily cleaved”