Biochemical Functions of Coenzyme Q10

By F. L. Crane. Journal of the American College of Nutrition, 2001

918 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/3b661f1cf24db2998ab82971d09289285b48826f

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Citations in the corpus

Acute exercise and oxidative stress: a 30 year history (2009, background): “In addition to its role in energy production, CoQ10 has also been shown to provide antioxidant protection either by directly scavenging superoxide produced during oxidative phosphorylation or by regenerating vitamin C, and vitamin E from their oxidized states [146].”
Role of oxidative modifications in atherosclerosis. (2004, background): “Coenzyme Q plays an important part as an electron and proton transfer agent in mitochondrial ATP production and in the maintenance of optimal pH of lysosomes (168).”
Statin-associated muscle symptoms: impact on statin therapy—European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management (2015, neutral): “80–95 Abnormal mitochondrial function with depletion of CoQ10 have been reported during statin therapy, even in asymptomatic statin users.”
A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness. (2011, background): “CoQ10 is not only a strong antioxidant that confers resistance to O&NS damage to mitochondria, but it is also a key molecule in the electron transport chain within the mitochondria (Butler et al., 2003; Crane, 2001).”
Biochemistry of Free Radicals and Antioxidants (2010, positive): “CoQ10 in its reduced form as the hydroquinone (ubiquinol) is a potent lipophilic antioxidant and is capable of recycling and regenerating other antioxidants such as tocopherol and ascorbate [64, 65].”