Mesenchymal-stem-cell-induced immunoregulation involves FAS-ligand-/FAS-mediated T cell apoptosis.

By K. Akiyama, Chider Chen, Dandan Wang, Xingtian Xu, Cunye Qu, T. Yamaza, T. Cai, Wanjun Chen, Lingyun Sun, S. Shi. Cell Stem Cell, 2012

650 citations recorded by the source corpus.

Subfields: Genetics, Pulmonary and Respiratory Medicine, Surgery

View Paper: https://www.semanticscholar.org/paper/3ae99454bdb96dc948a30d95f92995c2b7aef883

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. W. Fibbe
2. Maria Ester Bernardo
3. C. Gregory
4. Jeffrey L Spees
5. R. Lee

In Pulmonary and Respiratory Medicine

1. W. Fibbe
2. Maria Ester Bernardo

In Surgery

1. W. Fibbe
2. Maria Ester Bernardo
3. C. Gregory
4. Jeffrey L Spees
5. R. Lee

Citations in the corpus

• Mechanisms of mesenchymal stem/stromal cell function (2016, background): “ation of naive T cells into Treg cells that can promote systemic immune tolerance [39].”
• Mesenchymal stromal cells: sensors and switchers of inflammation. (2013, positive): “This effect translated into amelioration of the disease phenotype (Akiyama et al., 2012).”
• The secretion profile of mesenchymal stem cells and potential applications in treating human diseases (2022, background): “The chemotaxis mediated by cues from MSCs assists in recruiting T cells for Fas ligand (FasL)mediated apoptosis and diminishing excessive inflammatory reactions in treating autoimmune disorders, such as systemic sclerosis and colitis.(116) The chemotactic gradients have a short half-live and undergo”