Postrepression Activation of NF-κB Requires the Amino-Terminal Nuclear Export Signal Specific to IκBα

By Tony T. Huang, S. Miyamoto. Molecular and Cellular Biology, 2001

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IκBα and p65 Regulate the Cytoplasmic Shuttling of Nuclear Corepressors: Cross-talk between Notch and NFκB Pathways (2003, background): “Because I B is crucial for p65 cytoplasmic translocation (Huang and Miyamoto, 2001), we also investigated whether I B was able to bind SMRT in the presence or in the absence of transfected p65.”
Molecular Basis of NF-κB Signaling (2013, background): “The interaction between the NEMOZF and ubiquitin resembles previously solved interactions between α-helical ubiquitin-binding domains and ubiquitin; the amphipathic α-helix of the NEMO ZF binds to a hydrophobic patch centered around residue Ile44 of ubiquitin (12, 27, 38, 39, 46, 73, 102, 107, 108).”