A conditional tissue-specific transgene expression system using inducible GAL4

By Thomas Osterwalder, Kenneth S. Yoon, B. White, H. Keshishian. Proceedings of the National Academy of Sciences of the United States of America, 2001

777 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/38af5ec45b44d3e46a146b7c60f16774ba65c688

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Citations in the corpus

Trade‐offs between longevity and pathogen resistance in Drosophila melanogaster are mediated by NFκB signaling (2006, background): “S106-GS-Gal4 is an inducible Gal4 driver (GeneSwitch) expressed predominantly in the abdominal fat body (Osterwalder et al., 2001; Roman et al., 2001).”
Genetic dissection of neural circuits. (2008, neutral): “GECIs have been used in combination with two-photon microscopy in Drosophila (Wang et al., 2003, 2004) (Figures 6E–6G) and mice (Hasan et al., 2004; Garaschuk et al., 2007).”
GAL4 system in drosophila: A fly geneticist's swiss army knife (2002, background): “Inclusion of an intron in the construction of a UAS hairpin responder may aid in formation and transport of the dsRNA molecule (Kalidas and Smith, 2002; Reichhart et al., in this issue) (Fig.”
The Mushroom Body of Adult Drosophila Characterized by GAL4 Drivers (2009, background): “Therefore, additional temporal control is favorable to circumvent such a ‘‘developmental effect’’ and to restrict the transgene expression to the adult (e.g., GeneSwitch or the GAL80[ts] system) (McGuire et al., 2003; Oster- walder et al., 2001; Roman et al., 2001).”
Mg2+ Block of Drosophila (2012, neutral): “LTM was normal in both lines in the absence of RU486.”
Cdc42-Dependent Forgetting Regulates Repetition Effect in Prolonging Memory Retention. (2016, background): “…its role in forgetting, Cdc42 activity was manipulated in neurons through the acutely induced expression of two mutants of Cdc42 (Luo et al., 1994; Osterwalder et al., 2001): dominant-negative Cdc42(N17) for inhibiting endogenous activity by competing for upstream activators and constitutively…”
Genetic manipulation of genes and cells in the nervous system of the fruit fly (2011, methodology): “Plasmids for enhancer- and promoter-bashing are available for fusions with GAL4, hormonally controlled GAL4 and LexA, or fluorescent proteins (Osterwalder et al., 2001; Sharma et al., 2002; Roman and Davis, 2002; Apitz et al., 2004; Barolo et al., 2004; Pfeiffer et al., 2008; Petersen and Stowers,…”
Active Protection: Learning-Activated Raf/MAPK Activity Protects Labile Memory from Rac1-Independent Forgetting. (2018, positive): “To address this question, we first tested memory retention at different time points after one-session training in flies overexpressing the Raf-GOF transgene driven by a pan-neuronal and RU486 feeding-dependent inducible driver, elav-GS (Osterwalder et al., 2001).”