Cerebrocerebellar networks during articulatory rehearsal and verbal working memory tasks

By S. H. A. Chen, John E. Desmond. NeuroImage, 2005

371 citations recorded by the source corpus.

Converging evidence has implicated the cerebellum in verbal working memory. The current fMRI study sought to further characterize cerebrocerebellar participation in this cognitive process by revealing regions of activation common to a verbal working task and an articulatory control task, as well as regions that are uniquely activated by working memory. Consistent with our model's predictions, load-dependent activations were observed in Broca's area (BA 44/6) and the superior cerebellar hemisphere (VI/CrusI) for both working memory and motoric rehearsal. In contrast, activations unique to verbal working memory were found in the inferior parietal lobule (BA 40) and the right inferior cerebellum hemisphere (VIIB). These findings provide evidence for two cerebrocerebellar networks for verbal working memory: a frontal/superior cerebellar articulatory control system and a parietal/inferior cerebellar phonological storage system.

Subfields: Cognitive Neuroscience, Neurology

View Paper: https://www.semanticscholar.org/paper/38a4b8f92177134001f9d76a843d0aa7690f0bbf

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cognitive Neuroscience

In Neurology

Citations in the corpus

An fMRI investigation of syllable sequence production (2006, background): “Both the superior lateral and inferior cerebellar regions demonstrating complexity effects are in close proximity to regions studied by Desmond and colleagues (Desmond et al., 1997; Chen and Desmond, 2005; Kirschen et al., 2005).”
Evidence for topographic organization in the cerebellum of motor control versus cognitive and affective processing (2010, background): “Chen and Desmond (2005a, 2005b) have proposed that the superior cerebellum (lobules VI/Crus I) is involved in the articulatory control aspect of this task while the inferior cerebellum (lobules VIIB/VIIIA) is important for phonological storage.”
The Cerebellum and Cognition: Evidence from Functional Imaging Studies (2011, background): “parietal loop (right lobules VIIB and VIIIA and the inferior parietal lobule) is involved in the maintenance and storage of information [105].”
Distinct Cerebellar Contributions to Intrinsic Connectivity Networks (2009, background): “In humans, functional imaging studies have highlighted the role of crus I in executive functions, such as abstract reasoning (Monti et al., 2007), working memory (Chen and Desmond, 2005), information updating (Collette et al., 2007), and response selection (Desmond et al., 1998).”
Learning and Consolidation of Novel Spoken Words (2009, result): “This conclusion is supported by existing evidence concerning a role for these regions in verbal rehearsal (Chen & Desmond, 2005; Smith, Jonides, Marshuetz, & Koeppe, 1998) and speech production (Alario, Chainay, Lehericy, & Cohen, 2006; Bohland & Guenther, 2006).”
Functional topography in the human cerebellum: A meta-analysis of neuroimaging studies (2009, neutral): “To further investigate these ideas, Chen and Desmond (2005b) used eventrelated fMRI to study the differences in cerebellar activation during encoding, maintenance and retrieval in the Sternberg task.”
Consensus Paper: The Cerebellum's Role in Movement and Cognition (2013, background): “One explanation for secondary-specific motor activity during VWM is that this system supports inner speech mechanisms to facilitate VWM rehearsal [144 – 149 , 152].”
Functional Topography of the Cerebellum in Verbal Working Memory (2010, background): “Neuroimaging research has revealed that the superior/ lateral region of the cerebellum (Lobule VI/Crus I) is most active during the encoding phase of the Sternberg task, when the original array of letters are shown at the beginning of each trial (Chen and Desmond 2005b).”
From storage to manipulation: How the neural correlates of verbal working memory reflect varying demands on inner speech. (2012, background): “Accordingly, dissociative neural systems for phonological encoding versus rehearsal have been demonstrated in several event-related fMRI studies (Chang, Crottaz-Herbette, & Menon, 2007; Chein & Fiez, 2001; Chen & Desmond, 2005a, 2005b; Marvel & Desmond, 2010a).”
The primate cortico-cerebellar system: anatomy and function (2006, background): “Numerous reports also suggest associations between cerebellar pathology and disorders of higher function that cannot easily be explained by impairments in motor contro”
Functional topography of the cerebellum for motor and cognitive tasks: an fMRI study (2011, methodology): “…the paced auditory serial addition task (PASAT), the n-back task, and the Sternberg paradigm (e.g., Beneventi et al., 2007; Cardinal et al., 2008; Chen and Desmond, 2005a, b; Forn et al., 2008; Hautzel et al., 2009; Hayter et al., 2007; Honey et al., 2000; Kirschen et al., 2005; Kirschen et al.,…”