CRISPR-Cas immunity in prokaryotes

By L. Marraffini. Nature, 2015

795 citations recorded by the source corpus.

Subfields: Ecology, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/0b7e2b68e7883ad9cf3e574bec2b9cd9c7b37599

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Ecology

1. Eugene V. Koonin
2. Kira S. Makarova
3. Feng Zhang
4. Bernd Zetsche
5. Yuri I. Wolf

In Genetics

1. Eugene V. Koonin
2. Kira S. Makarova
3. Bernd Zetsche
4. Feng Zhang
5. Takanori Nakane
6. Jennifer A. Doudna

In Molecular Biology

1. Feng Zhang
2. Eugene V. Koonin
3. Kira S. Makarova
4. Bernd Zetsche
5. Min Wu
6. I. Slaymaker
7. Takanori Nakane
8. I. Fedorova

Citations in the corpus

• Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics (2022, background): “aeruginosa.(317,318) It is known that CRISPR-Cas systems provide adaptive immunity against the invasion of bacteriophages or plasmids.”
• Crystal structure of Cpf1 in complex with guide RNA and target DNA (2016, background): “INTRODUCTION The microbial adaptive immune system CRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPRassociated proteins) helps bacteria and archaea defend themselves against the invasion of foreign nucleic acids (Marraffini, 2015;Wright et al., 2016).”