Multiple newly identified loci associated with prostate cancer susceptibility

By R. Eeles, Z. Kote-Jarai, G. Giles, A. Olama, M. Guy, S. Jugurnauth, S. Mulholland, D. Leongamornlert, S. Edwards, J. Morrison and 36 more. Nature Genetics, 2008

884 citations recorded by the source corpus.

Subfields: Genetics, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/385a960345a3ceb24064ba724184fe01b77954a2

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In Genetics

Citations in the corpus

Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations (2010, background): “The biological interpretation of genome-wide association study (GWAS) signals [1–5] is very challenging since most candidate loci fall either in gene deserts or in regions with many equally plausible causative genes.”
Estimation of effect size distribution from genome-wide association studies and implications for future discoveries (2010, neutral): “Our analysis included 20 susceptibility loci for cancers, reported in studies based in the U”
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits (2009, background): “Although some of these aspects have been examined on a smaller scale for individual diseases such as type 2 diabetes (2), inflammatory bowel disease (3), and cancer (4), a comprehensive genome-wide analysis across all GWAS pub lished to date has not been conducted.”
Genetics and biology of prostate cancer (2018, background): “…is among themost heritable cancers (Lichtenstein et al. 2000); GWASs have identifiedmany prostate cancer susceptibility loci (Yeager et al. 2007; Eeles et al. 2008, 2009, 2013; Thomas et al. 2008;Gudmundsson et al. 2009; Yeager et al. 2009; Takata et al. 2010; Xu et al. 2012a; Schumacher et al.…”