Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health
By Kathryn E. Holt, H. Wertheim, R. Zadoks, S. Baker, C. A. Whitehouse, D. Dance, A. Jenney, Thomas Richard Connor, L. Hsu, J. Severin and 18 more. Proceedings of the National Academy of Sciences of the United States of America, 2015
1,213 citations recorded by the source corpus.
Subfields: Endocrinology, Food Science, Molecular Medicine
View Paper: https://www.semanticscholar.org/paper/3826bee6426b4994654834b76f3826c45c87d478
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Endocrinology
In Food Science
In Molecular Medicine
- Ryan R. Wick
- Kathryn E. Holt
- Rebekah M. Martin
- C. Giske
- M. Bachman
- T. Strateva
- Jacques Nicolas
- Clara Delahaye
Citations in the corpus
- Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae (2018, background): “A more recent study of isolates from the three phylogroups collected worldwide Frontiers in Cellular and Infection Microbiology | www.frontiersin.org 9 January 2018 | Volume 8 | Article 4 (n= 328) determined that∼50% of KpII isolates display an ESBL phenotype (Holt et al., 2015).”
- Rapid scoring of genes in microbial pan-genome-wide association studies with Scoary (2016, background): “Genome-wide association studies (GWAS) have in human medicine and genomics become a workhorse for linking genetic variants in a population with observed phenotypes, but bacterial GWAS have only very recently started to emerge [1–9].”
- Completing bacterial genome assemblies with multiplex MinION sequencing (2017, methodology): “Read-mapping pipelines can use Illumina reads to reliably identify single nucleotide polymorphisms, necessary for inferring phylogenies and understanding population structure [1].”
- Fast and flexible bacterial genomic epidemiology with PopPUNK (2018, background): “…in gene content underlie much phenotypic variation between bacteria, and these are correlated with core genome divergence in multiple species (Croucher et al. 2014b; Zhou et al. 2014; Holt et al. 2015; Aanensen et al. 2016) , motivating the use of this information in epidemiological typing.”
- Epidemic of carbapenem-resistant Klebsiella pneumoniae in Europe is driven by nosocomial spread (2019, background): “Core genome phylogenetic analysis revealed a partitioning into four species, supporting recent taxonomic classifications [15, 16] (Fig.”