NCLX is an essential component of mitochondrial Na+/Ca2+ exchange

By Raz Palty, W. F. Silverman, M. Hershfinkel, Teresa Caporale, S. Sensi, Julia Parnis, C. Nolte, D. Fishman, V. Shoshan-Barmatz, S. Herrmann and 2 more. Proceedings of the National Academy of Sciences of the United States of America, 2009

782 citations recorded by the source corpus.

Subfields: Molecular Biology, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/37c24ec499565758c1c030494caa2eb60a8d675e

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In Molecular Biology

1. M. Juhaszova
2. D. Zorov
3. Steven J. Sollott
4. E. Carafoli
5. Tito Calì
6. Denis Ottolini
7. M. Brini
8. Michael R Hamblin

Citations in the corpus

• Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. (2014, background): “166, 434) with recent molecular identification of the Ca(2) -uniporter (36, 105) and Ca(2) /2Na exchanger (332), the role of Ca(2) in ROS production in mitochondria remains controversial.”
• Neuronal calcium signaling: function and dysfunction (2014, background): “A mitochondrial NCX (NCLX) [87, 88] mediates the efflux of Ca 2+ from mitochondria, thus preventing it from reaching thermodynamic equilibrium.”