Amphiphilic block copolymers for drug delivery.

By Monica L. Adams, A. Lavasanifar, G. Kwon. Journal of Pharmacy and Science, 2003

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Strategies in the design of nanoparticles for therapeutic applications (2010, background): “The predominant strategy has been to adsorb or graft a hydrophilic polymeric coating, such as PEG, to the surface of the particl”
Block copolymer micelles: preparation, characterization and application in drug delivery. (2005, background): “Owing to its high aqueous solubility, high mobility and large exclusion volume [72], PEG imparts steric stability by minimizing the interfacial free energy of the micellar core and by impeding hydrophobic intermicellar attractions [73].”
Nano/micro technologies for delivering macromolecular therapeutics using poly(D,L-lactide-co-glycolide) and its derivatives. (2008, methodology): “Number of PLGA block and alternating copolymers have been synthesized consisting of PLGA alternating with hydrophilic moieties like poly(ethylene oxide), PEO or poly(ethylene glycol), PEG [30–33].”
Micellar carriers based on block copolymers of poly(ε-caprolactone) and poly(ethylene glycol) for doxorubicin delivery (2004, background): “core of the micelles is a carrier compartment that accommodates anti-tumor drugs, and the shell consists of a brush-like protective corona that stabilizes the nanoparticles in aqueous solution [3–5].”