Dietary intake of antioxidants and risk of Alzheimer disease.

By M. Engelhart, M. Geerlings, A. Ruitenberg, J. V. van Swieten, Albert Hofman, J. Witteman, Monique M. B. Breteler. Journal of the American Medical Association (JAMA), 2002

1,120 citations recorded by the source corpus.

Subfields: Biochemistry, Physiology, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/34f5bc578bd63a1987acae8e18661d84c3db7f5c

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In Biochemistry

Richard P. Mayeux

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Citations in the corpus

Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis (2014, background): “9%) found the relationship to be in the hypothesized direction in the entire population that was studied and for most outcomes of interest [176,178,182,184,189,193,194,197,198], while 5 found this relationship for specific antioxidants or some outcomes but not others [180,183,186,196,200,201] and 1 ”
Epidemiology of Alzheimer Disease (2012, positive): “Two studies found a lower risk of Alzheimer disease in individuals with a higher dietary intake of vitamin D (Engelhart et al. 2002; Morris et al. 2002).”
Vitamin C Function in the Brain: Vital Role of the Ascorbate Transporter (SVCT2) (2009, background): “ascorbate supplement use and reduced disease incidence [157,158] and also with disease-related markers of oxidative stress [159],”
Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: implications for diagnostic and therapeutic strategies. (2013, background): “Under genetic background and pathophysiological condition of AD, oxidative stress and this vicious circle are more prone to take place and have been demonstrated as an early event occurring before the appearance of senile plaques and onset of clinical manifestations (Bishop et al., 2010; Bonilla et ”
Expression of Nrf2 in Neurodegenerative Diseases (2007, positive): “Increased antioxidant activity confers protection in mouse and culture models (8, 9) and has been reported to lower the risk of AD (10, 11).”
The Rotterdam Study: 2010 objectives and design update (2007, background): “Moreover, several life style factors are associated with the risk of dementia and Alzheimer disease [191–193], suggesting that onset of dementia may at least partly be delayed or prevented.”
A Review: Inflammatory Process in Alzheimer's Disease, Role of Cytokines (2012, background): “Elderly French men and women with the lowest flavonoid intakes, on the other hand, had a 50% higher risk of developing dementia over the next 5 years than those with the highest intakes [214].”