Hyaluronan: from extracellular glue to pericellular cue

By B. Toole. Nature Reviews. Cancer, 2004

2,116 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/3488563c03cedbae83c9c1d8423aeb0c6b33a4a3

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. K. Girish
2. Peter C. Searson
3. H. Wiig
4. M. Swartz
5. K. Kemparaju

In Molecular Biology

1. H. Wiig
2. K. Girish
3. Peter C. Searson
4. M. Swartz
5. K. Kemparaju
6. Paolo P. Provenzano

Citations in the corpus

• Therapeutic Strategies for Enhancing Angiogenesis in Wound Healing (2018, background): “HA is a functional component of connective tissue ECM that plays a critical role in cell signaling, tissue development and maintenance of tissue health and homeostasis [285,286].”
• The blood-brain barrier: an engineering perspective (2013, background): “HA is a long unbranched polysaccharide with negatively charged disaccharide repeat units, and is unique amongst the glycosaminoglycans (GAGs) in that it is nonsulfated (Laurent and Fraser, 1992; Toole, 2004; Zimmermann and Dours-Zimmermann, 2008; Ananthanarayanan et al., 2011).”
• Interstitial fluid and lymph formation and transport: physiological regulation and roles in inflammation and cancer. (2012, background): “The role of hyaluronan in tumor growth and development has been realized for many years (219) and has been the topic of several extensive recent reviews (156, 473, 474).”
• Hyaluronan: A Simple Polysaccharide with Diverse Biological Functions (2013, background): “Enrichment of HA in tumors can be attributed to increased production by tumor cells themselves or by tumor-associated stromal cells through tumor–stroma crosstalk [124].”
• Hyaluronic Acid in the Third Millennium (2018, background): “During some environmental and pathological conditions, such as asthma, pulmonary fibrosis and hypertension, chronic obstructive pulmonary disease and rheumatoid arthritis, HMW HA is cleaved into LMW HA (2 × 104–106 Da), which has been shown to possess pro-inflammatory and pro-angiogenic activities [”
• Current development of biodegradable polymeric materials for biomedical applications (2018, background): “and biological properties mediate cellular signaling, morphogenesis, matrix organization, and wound repair.(66,67) In 1943,”