Engineering vascularized tissue

By Rakesh K. Jain, P. Au, Josh Tam, D. Duda, Dai Fukumura. Nature Biotechnology, 2005

810 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Vascularization and Angiogenesis in Tissue Engineering: Beyond Creating Static Networks. (2016, background): “This means that all of the cells need to be within a distance of 200 mm from a vessel, which is generally regarded as the diffusion limit of oxygen and nutrients within a tissue [5].”
Recent advances in bone tissue engineering scaffolds (2012, background): “In vivo conditions, supply of oxygen and nutrients are essential for the survival of growing cells and tissues within scaffolds [27].”
Tissue Engineering for Clean Meat Production (2019, background): “ECs and Vascularization Muscle tissues are rich in microvascular networks (Figure 2) (Jain et al., 2005; Guo et al., 2015).”
Thermal Inkjet Printing in Tissue Engineering and Regenerative Medicine (2012, background): “This approach has generated some significant successes in constructing avascular, aneural, alymphatic, thin, and hollow organs [6, 7].”
Vascularized Bone Tissue Engineering: Approaches for Potential Improvement (2012, background): “The importance of vascularization has been also demonstrated for the engineering of other tissues, such as muscle, nerve, and bone.(8,10,11) Various strategies have been attempted to enhance the establishment of vascular networks within engineered constructs for bone regeneration (Fig.”