Hydrogen sulfide mediates the vasoactivity of garlic

By G. Benavides, G. Squadrito, Robert W. Mills, Hetal D. Patel, T. Isbell, R. Patel, V. Darley-Usmar, J. Doeller, D. Kraus. Proceedings of the National Academy of Sciences of the United States of America, 2007

841 citations recorded by the source corpus.

Subfields: Biochemistry, Immunology, Plant Science

View Paper: https://www.semanticscholar.org/paper/33ffed0b32ae2f08ae82d2b7c123a1ab0e395d2d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. Rui Wang
2. S. Snyder
3. P. Nagy
4. P. Moore
5. Ling-Xia Li
6. C. Winterbourn
7. P. Rose
8. Z. G. Li

In Immunology

1. P. Nagy
2. C. Winterbourn
3. Rui Wang

In Plant Science

1. A. Slusarenko

Citations in the corpus

• Hydrogen sulfide and cell signaling. (2011, background): “Interestingly, garlic compounds such as diallyl sulfide (DAS), a possible H2S donor (89), can also downregulate NF-κB activation.”
• Redox chemistry of biological thiols (2010, background): “The protective role of H2S in cardiovascular disease was reported recently by several research groups [209,215–217].”
• Physiological implications of hydrogen sulfide: a whiff exploration that blossomed. (2012, background): “In fact, garlic and garlic-derived polysulfide can induce H2S production in biological membranes or intracellular milieu as long as the reduced thiols exist (43).”
• Allicin: Chemistry and Biological Properties (2014, background): “Since allicin decomposes rapidly to its degradation products, it has been shown that a complex reaction cascade with thiols (glutathione in particular) results in the release of hydrogen sulfide (H2S) [88] H2S, again, is a known potent gaseous signalling molecule in regard to blood-pressure regulati”
• H2S Signals Through Protein S-Sulfhydration (2009, background): “The vasodilating actions of garlic reflect H2S acting on ATPsensitive potassium channels (16).”