RNAcentral: a hub of information for non-coding RNA sequences

By B. Sweeney, Anton I. Petrov, Boris Burkov, Robert D. Finn, Alex Bateman, M. Szymanski, W. Karłowski, Jan Gorodkin, S. Seemann, J. Cannone and 51 more. Nucleic Acids Res., 2018

303 citations recorded by the source corpus.

Abstract RNAcentral is a comprehensive database of non-coding RNA (ncRNA) sequences, collating information on ncRNA sequences of all types from a broad range of organisms. We have recently added a new genome mapping pipeline that identifies genomic locations for ncRNA sequences in 296 species. We have also added several new types of functional annotations, such as tRNA secondary structures, Gene Ontology annotations, and miRNA-target interactions. A new quality control mechanism based on Rfam family assignments identifies potential contamination, incomplete sequences, and more. The RNAcentral database has become a vital component of many workflows in the RNA community, serving as both the primary source of sequence data for academic and commercial groups, as well as a source of stable accessions for the annotation of genomic and functional features. These examples are facilitated by an improved RNAcentral web interface, which features an updated genome browser, a new sequence feature viewer, and improved text search functionality. RNAcentral is freely available at https://rnacentral.org.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/32915f4e54d3a8add04241ffb5da0379494a6358

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In Molecular Biology

Citations in the corpus

The EMBL-EBI search and sequence analysis tools APIs in 2019 (2019, methodology): “RNAcentral (14) generates meta-data from their comprehensive ncRNA sequence collection that is indexed by EBI Search, which creates a cus-tomised view of these data using the EBI Search API.”