Circular RNA profile identifies circPVT1 as a proliferative factor and prognostic marker in gastric cancer.

By Jie Chen, Yan Li, Qiupeng Zheng, Chunyang Bao, Jian He, Bin Chen, Dongbin Lyu, B. Zheng, Yu Xu, Z. Long and 6 more. Cancer Letters, 2017

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CircRNA: functions and properties of a novel potential biomarker for cancer (2017, background): “Recent studies have shown that circRNAs participate in the initiation and progression of tumours [18, 19].”
Circular RNA cSMARCA5 inhibits growth and metastasis in hepatocellular carcinoma. (2018, background): “In fact, many studies have proved that circRNAs can function as sponges for microRNAs (miRNAs) [13-20] or bind to proteins[21, 22], and altered circRNA levels can result in aberrant expression of gene products that may contribute to cancer”
Circular RNAs: Promising Biomarkers for Human Diseases (2018, background): “CircPVT1 was found upregulated in GC tissues and suggested as an independent prognostic marker for overall survival and disease-free survival of patients with GC [43].”