In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes.
By Claudine Scolaro, A. Bergamo, L. Brescacín, R. Delfino, M. Cocchietto, G. Laurenczy, T. J. Geldbach, G. Sava, P. Dyson. Journal of Medicinal Chemistry, 2005
717 citations recorded by the source corpus.
Subfields: Oncology, Organic Chemistry
View Paper: https://www.semanticscholar.org/paper/31fd20dc315194c397f019ce53e9c0b5ffc7e707
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In Oncology
In Organic Chemistry
Citations in the corpus
- Organometallic Anticancer Compounds (2010, background): “The extend of this non-toxicity was proven in an in vivo study when healthy mice were treated at quite high doses with RAPTA compounds without triggering toxic side effects.(129) But, the most striking result observed was that both RAPTA-C and”
- ‘New Trends for Metal Complexes with Anticancer Activity’ (2008, background): “also showed the same low in vitro cytotoxicity but in vivo inhibition of lung metastases in CBA mice bearing MCa mammary carcinoma [49].”