Repression of transforming-growth-factor-β-mediated transcription by nuclear factor κB

By R. Nagarajan, Feifei Chen, Wei Li, E. Vig, M. Harrington, Harikrishna Nakshatri, Yan Chen. 2000

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Transactivation of C-Reactive Protein by IL-6 Requires Synergistic Interaction of CCAAT/Enhancer Binding Protein β (C/EBPβ) and Rel p501 (2001, background): “p65 has been shown to repress the transcriptional activity of glucocorticoid receptors (26–28), to inhibit expression of thea1(I) collagen gene (29) and of p53-dependent genes (30–32), and to repress TGFb-mediated transcription (33).”
Keratinocyte-fibroblast interactions in wound healing. (2007, background): “NFkB activation was shown to interfere with TGF-b signaling (Bitzer et al., 2000; Nagarajan et al., 2000; Verrecchia et al., 2000).”
Transforming Growth Factor- 1 to the Bone (2005, background): “In addition, Smad7 expression was shown to be decreased by TNF- and NF- B in human embryonic kidney 293 cells through competition of NF- B with Smad3 (a stimulator of Smad7 expression) for binding to p300 (294).”