LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes.

By B. Laffitte, J. Repa, S. Joseph, Damien C. Wilpitz, H. R. Kast, D. Mangelsdorf, P. Tontonoz. Proceedings of the National Academy of Sciences of the United States of America, 2001

694 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology, Surgery

View Paper: https://www.semanticscholar.org/paper/313b0cef00cd6f69be48fc14591a5759993397f7

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. P. Tontonoz

In Molecular Biology

1. A. Calkin
2. P. Tontonoz

In Surgery

1. A. Calkin
2. P. Tontonoz
3. I. Tabas

Citations in the corpus

• Cholesterol efflux and atheroprotection: Advancing the concept of reverse cholesterol transport (2012, background): “LXRs also increase the endogenous expression of macrophage apoE, which increase cholesterol efflux by interaction with the ABCA1 transporter (53).”
• Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR (2012, background): “LXRs induce expression of a cluster of apolipoprotein genes ( APOE , APOC1 , APOC2 and APOC4 ) via activation of a multienhancer regio”