Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin.
By Wei-Shiung Yang, Wei-Jei Lee, Tohru Funahashi, Sachiyo Tanaka, Yuji Matsuzawa, Chia-Ling Chao, Chi-Ling Chen, Tong-Yuan Tai, Lee-Ming Chuang. Journal of Clinical Endocrinology and Metabolism, 2001
1,235 citations recorded by the source corpus.
Subfields: Cardiology and Cardiovascular Medicine, Epidemiology, Immunology
View Paper: https://www.semanticscholar.org/paper/30f0e9942e28cd8d3c6b367736d4f0be5bf393c3
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Citations in the corpus
- Omentin Plasma Levels and Gene Expression Are Decreased in Obesity (2007, background): “Expression of adipose-derived factors such as leptin (27), plasminogen activator inhibitor 1 (28), and adiponectin (29,30) are modulated by obesity.”
- Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans. (2003, background): “Previous studies have demonstrated that the reduced circulating adiponectin levels could be reversed partially after induction of weight loss in obese and in insulin-resistant subjects (21, 40) as well as after treatment with insulin-sensitizing drugs such as thiazolidinediones (8, 27).”
- Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin. (2004, background): “Weight reduction achieved by low-calorie diet also increases plasma adiponectin in both nondiabetic and diabetic patients (110).”
- Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism. (2003, background): “Adiponectin, however, unlike other adipocytokines, is decreased in adiposity (3,4) and increases after weight reduction (5).”
- Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression. (2003, methodology): “In addition, plasma adiponectin levels increase following weight loss (33).”
- Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial. (2003, background): “IL-6 increases plasma FFA and fat oxidation in humans,(21) whereas plasma adiponectin levels are positively associated with whole-body insulin sensitivity.(22) Interestingly, there is some evidence that adiponectin may participate in fatty acid and energy homeostasis.”
- Minireview: adiposity, inflammation, and atherogenesis. (2003, background): “Serum adiponectin levels are low in obese subjects but increase upon weight loss (25, 26).”
- Adiponectin Regulation and Function (2018, neutral): “In support of this, bariatric surgery-induced weight loss results in a significant increase in the circulating concentration of adiponectin (173, 387).”
- Plasma Adiponectin, Body Mass Index, and Mortality in Patients With Chronic Heart Failure (2005, neutral): “Ischemic heart disease 60 (38) 63 (41) 47 (28) 0.”
- Insulin resistance and chronic cardiovascular inflammatory syndrome. (2003, positive): “Weight reduction leads to increases of its plasma levels (296), and adiponectin administration reverses insulin resistance associated with obesity (297).”