Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer

By Akihiro Fujimoto, Mayuko Furuta, Y. Totoki, Tatsuhiko Tsunoda, Mamoru Kato, Y. Shiraishi, Hiroko Tanaka, H. Taniguchi, Y. Kawakami, M. Ueno and 41 more. Nature Genetics, 2016

632 citations recorded by the source corpus.

Subfields: Cancer Research, Epidemiology, Hepatology

View Paper: https://www.semanticscholar.org/paper/30633ea78dc90a6a8601b62aa9c4547c7016a2c8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Peter J. Campbell
2. S. Nik-Zainal
3. Ludmil B. Alexandrov
4. Michael R. Stratton
5. Jichun Yang
6. Charles Swanton
7. Nicholas McGranahan

In Hepatology

1. B. Sangro
2. Ron Shamir
3. Nimrod Rappoport

Citations in the corpus

• Advances in immunotherapy for hepatocellular carcinoma (2021, background): “I.M. receives funding from MINECO SAF2014-52361-R and SAF 2017- 83267-C2-1R; Worldwide Cancer Research Grant (15-1146); the Asociacion Española Contra el Cancer (AECC) Foundation under grant GCB15152947MELE; and the European Union’s Horizon 2020 Program (grant agreement no. 635122 PROCROP).”
• Deep Learning based multi-omics integration robustly predicts survival in liver cancer (2017, background): “These samples belong to a Japanese population primarily infected with HBV/HCV (31).”
• Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma (2017, neutral): “We report the Chi-square and Binomial test p values for the difference in the ratio of inactivating variation in each gene compared with the background rate of the entire cohort (Table S2B).”
• Mutational signatures associated with tobacco smoking in human cancer (2016, background): “Recent reports have shown a smoking associated elevation of signature 4 in liver cancer (26) and elevation of signature 5 in bladder cancer (23).”
• Long Non-Coding RNA in the Pathogenesis of Cancers (2019, background): “In one study, it was reported that although cell growth is not affected after knockdown of NEAT1 in HepG2, cell invasion is significantly decreased [242].”