Cellular signaling by fibroblast growth factor receptors.
By V. P. Eswarakumar, I. Lax, Joseph Schlessinger. Cytokine & growth factor reviews, 2005
1,938 citations recorded by the source corpus.
Subfields: Genetics, Molecular Biology, Oncology
View Paper: https://www.semanticscholar.org/paper/2f144873a7e4d36f8673a6abb1b0dc4dcc37f4f1
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Citations in the corpus
- Protein tyrosine phosphatases: from genes, to function, to disease (2006, background): “In an intriguing symmetry with the regulation of RPTK”
- Fate decision of mesenchymal stem cells: adipocytes or osteoblasts? (2016, background): “FGFs have been implicated in both adipogenesis and osteogenesis.(61) The FGF family consists of 23 structurally related members that are ubiquitously expressed in almost all tissue types.”
- Fibroblast growth factor signalling: from development to cancer (2010, background): “Phosphorylated tyrosine residues on the receptor function as docking sites for adaptor proteins, which themselves may also be directly phosphorylated by FGF”
- Fibroblast Growth Factors: Biology, Function, and Application for Tissue Regeneration (2010, background): “Unlike other growth factors, FGFs act in concert with heparin or heparan sulfate proteoglycan (HSPG) to activate FGFRs and induce the pleiotropic responses that lead to a variety of cellular responses induced by this large family of growth factors [14].”
- Development of the endochondral skeleton. (2013, background): “WNTinduced G-protein-coupled phosphatidylinositol signaling and PKCd activation have been shown to promote osteoblast differentiation by stimulating the progression from RUNX2- to OSX-positive cells through an unknown mechanism (Tu et al. 2007).”
- Building strong bones: molecular regulation of the osteoblast lineage (2011, background): “Most FGFs function by binding to cell surface Tyr kinase FGF receptors (FGFRs; FGFR1–FGFR4 in humans and mice), leading to the phosphorylation of a range of signalling proteins and the activation of multiple signalling modules, including mitogen-activated protein kinase (MAPK), phosphoinositide 3-ki”
- Kinase-targeted cancer therapies: progress, challenges and future directions (2018, background): “EGFR represent RTKs family as the well-studied kinase, implicated in several human cancers including lung cancer [62], glioblastoma [63], breast cancer [64], cervical carcinoma [65] and related mutations [66].”