NOBEL LECTURE: Worms, Life and Death
By H. Horvitz. 2003
109 citations recorded by the source corpus.
View Paper: https://www.semanticscholar.org/paper/2efffca4f876bd797e728a0bdf7ae848da3c0082
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- Guido Kroemer
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- Seamus J. Martin
- Bert Vogelstein
Citations in the corpus
- Cell death by necrosis: towards a molecular definition. (2007, background): “Towards necrosis-specific molecular processes? Mutagenesis studies have identified genes that are required for apoptotic cell death, such as ced3, ced4 and ced9 in C. elegans and their homologs in other species [ 27 ].”
- Cancer genes and the pathways they control (2004, background): “This concept is very familiar to geneticists studying yeast, flies, mice or worms—there are almost always a variety of genes that, when altered, lead to similar phenotype”
- Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology (2008, background): “This is best exemplified by the mechanistic elucidation of the apoptotic pathway in C. elegans, for which the 2002 Nobel Prize in Physiology or Medicine was awarded (Hengartner and Horvitz, 1994; Horvitz, 2003; Sulston, 2003).”
- Caspase-independent cell death (2005, background): “In Caenorhabditis elegans and in Drosophila melanogaster , genetic inactivation or inhibition of caspases prevents cell death, leading to the persistence of many cells that otherwise would have died during developmen”
- Apoptosis and cancer: the genesis of a research field (2009, background): “His Nobel lecture provides a fascinating insight into his contribution to the fiel”
- Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies (2006, unknown): “dtd" [ ]> Apoptosis, or programmed cell death, results from the activation of an evolutionarily conserved genetic pathwa”
- The apoptosome: signalling platform of cell death (2007, methodology): “Fly and nematode apoptosomes Studies using the nematode Caenorhabditis elegans formed the basis of the discovery that apoptosis is a genetically programmed pathwa”