Dietary fat reduction and breast cancer outcome: interim efficacy results from the Women's Intervention Nutrition Study.

By R. Chlebowski, G. Blackburn, C. Thomson, D. Nixon, A. Shapiro, M. Hoy, M. Goodman, A. Giuliano, N. Karanja, P. McAndrew and 13 more. Journal of the National Cancer Institute, 2007

751 citations recorded by the source corpus.

Subfields: Cancer Research, Oncology, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/2ebf459e2b0877d70aa2a54b2de631d1ce7c9084

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In Cancer Research

1. I. Tannock

In Oncology

1. M. Hung
2. Bostjan Seruga
3. Vickie E. Baracos
4. J. Slingerland
5. L. J. Bernstein
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Citations in the corpus

• Nutrition and physical activity guidelines for cancer survivors (2012, methodology): “initial weight) reduced the risk of recurrence among postmenopausal breast cancer survivors (especially those with estrogen receptor [ER]-negative tumors).(91) However, this trial was not designed to specifically address weight loss, and the results are confounded by the impact of a low-fat diet tha”
• American Cancer Society/American Society of Clinical Oncology Breast Cancer Survivorship Care Guideline (2016, positive): “Data from the two large RCTs of diet interventions in breast cancer survivors suggest that dietary change sufficient to result in weight loss may be needed to favorably impact breast cancer recurrence and prognosis.(210,211) According to the ACS Nutrition and Physical Activity Guidelines, alcohol co”
• Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer. (2009, background): “1%).(33,34) There is no insulin level analysis available, but the result is consistent with the notion that factors other than estrogen, such as insulin, are important in this ER- and PR-negative subset.”
• Effect of obesity on survival of women with breast cancer: systematic review and meta-analysis (2010, background): “A recent RCT showed that reducing dietary fat intake improves relapse-free survival of breast cancer, despite only a modest effect on weight [46].”
• ESPEN guidelines on nutrition in cancer patients. (2017, background): “Two large RCTs counselling breast cancer survivors to reduce fat intake (WINS trial, 2437 women) or to simultaneously decrease the intake of fat and increase the intake of vegetables (WHEL trial, 3088 women) after 5e7 years of observation could not reliably detect an effect on recurrence rates or mo”
• Cytokines and their relationship to the symptoms and outcome of cancer (2008, result): “By contrast, in the Women's Intervention Nutrition Study, a large randomized trial that investigated lifestyle intervention with reduced dietary fat intake, there was a decreased probability of breast cancer recurrence, especially in women with ER-negative breast cancer”
• Obesity and adverse breast cancer risk and outcome: mechanistic insights and strategies for intervention (2017, background): “98).(188) In contrast, in the Women’s Healthy Eating and Living (WHEL) Study of a high-fiber, fruits and vegetables”