Mechanisms of migraine aura revealed by functional MRI in human visual cortex

By N. Hadjikhani, M.M. Sanchez, Del Rio, O. Wu, D. Schwartz, D. Bakker, Bruce Fischl, K. Kwong, F. Cutrer, Bruce R. Rosen and 3 more. Proceedings of the National Academy of Sciences of the United States of America, 2001

1,488 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Psychiatry and Mental health, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/2e87b54f9a7bae1f8cc2dac3f8c1ac5625f9b755

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Citations in the corpus

PATHOPHYSIOLOGY OF MIGRAINE (2006, methodology): “Human aura has been well described using functional imaging methods to behave in a similar fashion (Hadjikhani et al, 2001).”
Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, CSD, sensitization and modulation of pain (2013, background): “First identified by Leão [67] in the rabbit, this distinctive electrophysiological phenomenon has been correlated with the visual aura that precedes the onset of headache in migraine [18,43,49,65,96].”
Pathophysiology of Migraine: A Disorder of Sensory Processing. (2017, methodology): “Recent studies supporting CSD in human brain during migraine aura (366, 702) only use blood flow evidence rather than neuronal changes, which is what technically defines CSD, and merely provide more sophisticated technology to measure the response than the original study from the 1980s (640).”
Perivascular nerves and the regulation of cerebrovascular tone. (2006, background): “Indeed, it was recently shown in human or animal models that cortical spreading depression, a wave of cortical depolarization that underlies migraine aura (17) and, possibly, also migraine without aura (31), activates trigeminovascular afferents and initiates a cascade of events that culminate into ”
Clinical Relevance of Cortical Spreading Depression in Neurological Disorders: Migraine, Malignant Stroke, Subarachnoid and Intracranial Hemorrhage, and Traumatic Brain Injury (2011, methodology): “…blood flow (CBF) in patients during migraine attacks showed what was termed a ‘spreading oligemia’, a wave of reduced blood flow that propagated across the brain at the same rate and with the same signs of vascular impairment as CSD (Olesen et al, 1981; Lauritzen, 1994; Hadjikhani et al, 2001).”
Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model (2002, background): “Recent blood oxygenation level-dependent (BOLD) functional magnetic resonance imagin”