SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN.

By T. Le, L. Pham, Matthew E. R. Butchbach, Honglai Zhang, U. Monani, D. Coovert, Tatiana O. Gavrilina, L. Xing, G. Bassell, A. Burghes. Human Molecular Genetics, 2005

615 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/214b9d349b22e4af7890418a5161e08faf92790e

Citations in the corpus

• SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing. (2008, unknown): “For this, we used a moderate SMA mouse model corresponding to a type II SMA phenotype (Le et al., 2005), as the affected animals survive for up to 14 days after birth, which allows the collection of various tissues at different stages as the disease progresses.”