Continuous inertial focusing, ordering, and separation of particles in microchannels

By D. Di Carlo, D. Irimia, R. Tompkins, Mehmet Toner. Proceedings of the National Academy of Sciences of the United States of America, 2007

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Particle focusing in microfluidic devices (2010, methodology): “Reprinted from Di Carlo et al. (2007) with permission from PNAS, National Academy of Sciences Fig. 10 Inertial focusing of 7 lm polymer beads in a straight multiorifice microchannel at different particle Reynolds numbers, Rep.”
Label-free cell separation and sorting in microfluidic systems (2010, background): “Lastly, their independence from external force fields eases their integration into massively parallel systems [65, 73].”
Particle inertial focusing and its mechanism in a serpentine microchannel (2014, background): “Di Carlo et al. (2007) introduced an asymmetric serpentine channel to focus particles into one streak in 2D (top view), and later, this asymmetric serpentine channel was combined with a straight section to successfully focus particles in 3D.”
Inertial Focusing for Tumor Antigen–Dependent and –Independent Sorting of Rare Circulating Tumor Cells (2013, methodology): “After the magnetic labeling of cells in whole blood, this capture platform integrates three sequential microfluidic technologies within a single automated system: (i) debulking by separation of nucleated cells, including CTCs and white blood cells (WBCs), from red blood cells (RBCs) and platelets us”