A microfluidic device for a pharmacokinetic-pharmacodynamic (PK-PD) model on a chip.

By J. Sung, C. Kam, M. Shuler. Lab on a Chip, 2010

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Microfluidic Devices for Drug Delivery Systems and Drug Screening (2018, methodology): “A useful programmable valve-actuated microfluidic device has been developed to generate anisotropic elongated particles of the same length, variable bonding angles, pre-designable size sequence and chemical order [77].”
From Three-Dimensional Cell Culture to Organs-on-Chips (2011, methodology): “This microﬂuidic system was later modiﬁed to incorporate 2D and 3D cultures of adipocytes, cancer cells and bone marrow stem cells to study drug accumulation, distribution, metabolism and toxicity [75 – 77].”
Biology-inspired Microphysiological System Approaches to Solve the Prediction Dilemma of Substance Testing (2016, unknown): “The layout of the µCCA has progressed over the years (Mahler et al., 2009a,b, 2012; Sung et al., 2010; Sung and Shuler, 2010).”