Substrate Specificities of MexAB-OprM, MexCD-OprJ, and MexXY-OprM Efflux Pumps in Pseudomonas aeruginosa

By N. Masuda, E. Sakagawa, S. Ohya, N. Gotoh, H. Tsujimoto, T. Nishino. Antimicrobial Agents and Chemotherapy, 2000

691 citations recorded by the source corpus.

Subfields: Epidemiology, Molecular Medicine, Pharmacology

View Paper: https://www.semanticscholar.org/paper/2c4638c80c149ec467be0345562022326ada02f9

How researchers see this paper

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In Epidemiology

1. Gerard D. Wright
2. H. Nikaido

In Molecular Medicine

1. L. Piddock
2. Gerard D. Wright
3. H. Nikaido

In Pharmacology

1. Gerard D. Wright
2. H. Nikaido

Citations in the corpus

• Clinically Relevant Chromosomally Encoded Multidrug Resistance Efflux Pumps in Bacteria (2006, background): “While there are some substrates exported by all four systems, the MexXY system exports aminoglycosides as well, whereas the MexAB-OprM system also exports certain -lactams, including carbenicillin (122) (Table 1).”
• Tetracycline Antibiotics and Resistance. (2016, neutral): “…oxytetracycline, tigecycline MexJK: tetracycline MexXY-OprM: tetracycline, minocycline, doxycycline, chlortetracycline, oxytetracycline, tigecycline Masuda et al. 2000; Morita et al. 2001; Chuanchuen et al. 2002; Dean et al. 2003; Schweizer 2003 P. mirabilis RND AcrAB: tigecycline, minocycline…”