Adult stem cells for tissue repair - a new therapeutic concept?

By M. Korbling, Z. Estrov. New England Journal of Medicine, 2003

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Stem cell origin of cancer and differentiation therapy. (2004, background): “Ii is this cell in the adult that offers new approaches to replacement of damaged tissue not previously considered possible [62].”
Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. (2005, background): “systems can be overwhelmed if tissue damage is more severe, leading to extensive and often permanent organ damage (15).”
Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. (2005, result): “This observation is consistent with the hypothesis that the intratumoral integration of exogenously delivered hMSCs is a recapitulation of the natural recruitment of endogenous, circulating hMSCs to aid in the process of stroma formation and tissue remodeling and suggests that hMSCs may contribute t”