The pros, cons, and many unknowns of probiotics

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How researchers see this paper

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The Bidirectional Relationship of Depression and Inflammation: Double Trouble (2020, background): “In addition, there is evidence for the role of probiotics in regulating behaviors, although the efficacy of probiotics in humans remains questionable (Suez et al., 2019).”
Short-chain fatty acids: linking diet, the microbiome and immunity (2024, positive): “The selective use of prebiotics and probiotic bacteria and bacterial communities can optimize niches for butyrogenic bacteria 163 .”
Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention (2019, background): “, although in this case too, it is highlighted the weakness of the existing data (124).”
Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment (2023, positive): “19 Given antibiotic (ABX) treatment negatively impacts responses to cancer immunotherapy 11,12,16,20 and probiotics are typically supplemented daily, 19 we treated non-ABX-treated speciﬁc-pathogen-free (SPF) mice with selected bacterial taxa via daily oral gavage (OG).”