Significance of CD90+ cancer stem cells in human liver cancer.

By Z. Yang, D. Ho, M. Ng, C. Lau, W. Yu, P. Ngai, P. Chu, C. Lam, R. Poon, S. Fan. Cancer Cell, 2008

1,228 citations recorded by the source corpus.

Subfields: Cancer Research, Hepatology, Oncology

View Paper: https://www.semanticscholar.org/paper/2af986c5f55bfedf2e78f92ee5b773b93cea4a44

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. W. Zou
2. G. Lindeman
3. Jane E. Visvader

In Hepatology

1. Jane E. Visvader

In Oncology

1. Jane E. Visvader
2. G. Lindeman
3. T. Welling
4. W. Zou
5. Lieping Chen
6. Zena Werb

Citations in the corpus

• Identification of Gastric Cancer Stem Cells Using the Cell Surface Marker CD44 (2009, methodology): “Based on previous published reports regarding CSCs in solid tumors [7–21], the following markers were studied: CD24, CD44, CD133, and CD166.”
• MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis. (2012, neutral): “Similarly, the expression of various selected oncofetal genes, namely Afp , Igf2 , and Src , together with the cancer stem cell marker genes Prom1 , Thy1 , and Epcam , could be first detected in the livers of young Mir122a –/– mice, and this was followed by further increases in the expression of the”
• Cancer stem cells in solid tumours: accumulating evidence and unresolved questions (2008, background): “In hepatocellular cancer, CSCs that might directly contribute to metastasis (circulating THY1 + CSC-like cells) have been detected in patients with liver cancer and could generate tumours in immunocompromised mic”
• Mechanisms of chemoresistance in cancer stem cells (2013, background): “Following this study, a number of reports have identified CSCs in solid tumors based on other surface markers such as CD133, EpCAM and CD90 as well as phenotypic markers such as side population (SP) or aldehyde dehydrogenase (ALDH) activity [9-13].”
• Tumor-Associated Macrophages Produce Interleukin 6 and Signal via STAT3 to Promote Expansion of Human Hepatocellular Carcinoma Stem Cells (2014, background): “CD90 and CD24 were identified in some primary tumor samples and also may represent populations enriched for stem cell capacity.(15,16) Several reports have attempted to describe surface markers of HCC CSCs, including EpCAM, CD133, CD90, and CD24.”