Role of reactive oxygen species (ROS) in apoptosis induction

By H. Simon, A. Haj-Yehia, F. Levi‐Schaffer. Apoptosis, 2000

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How researchers see this paper

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Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment (2009, neutral): “ROS production has been associated with apoptotic cell death in numerous pathologic conditions such as stroke, inﬂammation, and ischemia (101).”
Reactive oxygen species in tumor progression. (2005, background): “Oxidation of mitochondrial pores by ROS may contribute to cytochrome C release due to the disruption of mitochondrial membrane potential (35).”
Biochemistry of Free Radicals and Antioxidants (2010, neutral): “Oxygen-centered non-radicals are hydrogen peroxide (H 2 O 2 ) and singlet oxygen ( 1 O 2 ), Hypochlorous acid and Ozone [14, 15].”
Oxidative Stress and Lipid Peroxidation Products in Cancer Progression and Therapy (2012, background): “Apoptosis is linked to an increase in mitochondrial oxidative stress that causes cytochrome c release and the consequent activation of caspases and cell death [68, 69].”
Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy (2012, neutral): “There are three major ways by which a cancer cell can die: apoptosis, necrosis, and autophagy (283, 285, 329).”