Ascorbic acid: metabolism and functions of a multi-facetted molecule.

By N. Smirnoff. Current opinion in plant biology, 2000

779 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/28fe822a9ddde8f92260abd471522c0fc4094089

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In Nutrition and Dietetics

Citations in the corpus

Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants. (2010, background): “In chloroplast, ASH acts as a cofactor of violaxantin de-epoxidase thus sustaining dissipation of excess excitation energy [211].”
Ascorbate and Glutathione: The Heart of the Redox Hub1 (2011, background): “As mentioned above, ascorbate participates in phenoxy radical-mediated cross-linking of cell wall components, leading to cell wall stiffening (Smirnoff, 2000).”
Phenolic compounds and their antioxidant activity in plants growing under heavy metal stress (2006, background): “This is the most important peroxidase in H2O2 detoxification operating both in cytosol and chloroplasts [15, 28].”
Reactive oxygen species in plants: their generation, signal transduction, and scavenging mechanisms (2011, background): “Under physiological conditions, AA exists mostly in the reduced form (90% of the ascorbate pool) in chloroplasts (Smirnoff, 2000).”
Ascorbic Acid-A Potential Oxidant Scavenger and Its Role in Plant Development and Abiotic Stress Tolerance (2017, background): “Introgression of this enzyme in wild-type Solanum pennellii shows that MDHAR activity enhances AsA levels and improves shelf life in tomato fruit experiencing freezing stress.”
Regulation of Ascorbate-Glutathione Pathway in Mitigating Oxidative Damage in Plants under Abiotic Stress (2019, background): “Ascorbate becomes oxidized during ROS scavenging, electron donation to photosystem II (PSII), violaxanthin de-epoxidation, and α-tocopherol reductive quenching [69,70].”
Reactive Oxygen Species (ROS) Generation and Detoxifying in Plants (2014, background): “…that the presence of H2O2 in the apoplast plays a positive role, i.e., it is toxic for pathogens, plays an active role in gene transcription and systemic acquired resistance, and limits the spread of invading organisms by cell death around the infected cells (Horemans et al., 2000; Smirnoff, 2000).”
Reactive oxygen species homeostasis and signalling during drought and salinity stresses. (2010, background): “AsA is an important antioxidant that serves as an electron donor to many important reactions (Smirnoff & Pallanca 1996; Noctor & Foyer 1998; Asada 1999; Smirnoff 2000; Mano, Hideg & Asada 2004; Ivanov et al. 2005; Shao et al. 2008).”
Regulation and function of ascorbate peroxidase isoenzymes. (2002, background): “review, knowledge about AsA metabolism, including the AsA synthetic pathway and the AsA regeneratory cycle in plant cells, has greatly increased within the past few years (Smirnoff, 2000).”
Copper accumulation, synthesis of ascorbate and activation of ascorbate peroxidase in Enteromorpha compressa (L.) Grev. (Chlorophyta) from heavy metal‐enriched environments in northern Chile (2003, neutral): “ASC by ROS (Smirnoff 2000).”
Nitric oxide as a bioactive signalling molecule in plant stress responses (2007, background): “Taking into consideration the fact that ascorbic acid (AsA) is a quantitatively dominant antioxidant in plant cells [126], it is possible that AsA participates in ONOO decomposition also in plant cells.”
Antioxidants, oxidative damage and oxygen deprivation stress: a review. (2003, background): “Under physiological conditions AA exists mostly in the reduced form (90 % of the ascorbate pool) in leaves and chloroplasts (Smirnoff, 2000); and its intracellular concentration can build up to millimolar range (e.g. 20 mM in the cytosol and 20±300 mM in the chloroplast stroma (Foyer and Lelandais,…”
Gene Expression Profiles during the Initial Phase of Salt Stress in Rice (2001, background): “…peroxidases, which exist in compartment-specific isoforms and are induced by reactive oxygen species, are important scavengers of cytosolic hydrogen peroxide produced under conditions of stress, and their functions have been documented both biochemically and in transgenic studies (Smirnoff, 2000).”
Increasing Ascorbic Acid Content and Salinity Tolerance of Cherry Tomato Plants by Suppressed Expression of the Ascorbate Oxidase Gene (2019, background): “One of the most important antioxidants in plants is ascorbic acid (AA), and this molecule is a major contributor to cellular redox state [30].”