Ovarian aromatase and estrogens: a pivotal role for gonadal sex differentiation and sex change in fish.

By Y. Guiguen, A. Fostier, F. Piferrer, Ching-Fong Chang. General and Comparative Endocrinology, 2010

670 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Sex Control in Fish: Approaches, Challenges and Opportunities for Aquaculture (2015, positive): “Cyp19a encodes for gonadal aromatase, which catalyses the conversion of androgens into estrogens and is thought to play a pivotal role in sex differentiation and sex change in fish [31].”
Effects of climate change on fish reproduction and early life history stages (2011, background): “Higher temperatures inhibit arom activity and drive sex determination towards the male phenotype (reviewed by Guiguen et al. 2010).”
Spermatogenesis in fish. (2010, background): “is possible in fish (Guiguen et al., 2010), it moreover seems that the somatic precursor cell population can assume male (Sertoli) or female (granulosa) cell fate.”
Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation. (2009, neutral): “…in Freemartins, or when fetal ovaries are grafted to the kidney capsule, in adult XX mice carrying mutations in both estrogen receptors or in the aromatase gene (Cyp19a1), or in Sertoli/Leydig tumors in postmenopausal women (Couse et al., 1999; Guiguen et al., 2009; Sekido and Lovell-Badge, 2009).”