Modern synthetic methods for fluorine-substituted target molecules.

By M. Shimizu, T. Hiyama. Angewandte Chemie, 2004

672 citations recorded by the source corpus.

Subfields: Organic Chemistry, Pharmaceutical Science

View Paper: https://www.semanticscholar.org/paper/27e78801d52596d7f55e413dd68f7f7509dcb230

Citations in the corpus

• Catalysis for Fluorination and Trifluoromethylation (2011, neutral): “Similar to incorporation of fluorine, the introduction of trifluoromethyl (CF 3 ) groups into organic molecules can substantially alter their properties, such as metabolic stability, lipophilicity, and ability to penetrate the blood-brain barrier 1–4, 46, 47 .”