Antibody-enabled small-molecule drug discovery

By A. Lawson. 2012

79 citations recorded by the source corpus.

Subfields: Molecular Biology, Organic Chemistry, Radiology, Nuclear Medicine and Imaging

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Sarel Jacob Fleishman
2. Gideon Lapidoth
3. Anima Anandkumar
4. Weili Nie
5. Jaime Prilusky
6. Arash Vahdat
7. Thomas F. Miller
8. Jake Parker

In Organic Chemistry

1. Sarel Jacob Fleishman

In Radiology, Nuclear Medicine and Imaging

1. Sarel Jacob Fleishman
2. Gideon Lapidoth
3. Jaime Prilusky
4. Arash Vahdat
5. Jake Parker

Citations in the corpus

• Dynamic-Backbone Protein-Ligand Structure Prediction with Multiscale Generative Diffusion Models (2022, background): “Proposing ligands that selectively target protein conformations has become an increasingly important strategy in small-molecule-based therapeutics [4–6].”
• Therapeutic peptides: current applications and future directions (2022, background): “High serum fasting peptide YY (3-36) is associated with obesity-associated insulin resistance and type 2 diabetes.”
• AbPredict 2: A server for accurate and unstrained structure prediction of antibody variable domains (2018, background): “Owing to their versatility, antibodies are by far the most important class of protein used in biomedical research(Hattori et al., 2010; Nogi et al., 2008),(Lawson, 2012) and clinical applications(Li & Zhu, 2010; Reichert & Valge-Archer, 2007; Vezina, Cotreau, Han, & Gupta, 2017).”