Corrigendum: 3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets

By Amanda Birmingham, E. Anderson, A. Reynolds, Diane Ilsley-Tyree, D. Leake, Yuriy Fedorov, S. Baskerville, E. Maksimova, K. Robinson, J. Karpilow and 2 more. Nature Methods, 2007

127 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/277ffc1ee5e8b3267caf0ac8b38cbe0c0809adb2

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In Molecular Biology

Citations in the corpus

Transcriptome engineering with RNA-targeting Type VI-D CRISPR effectors (2018, unknown): “Existing RNA interference technologies, which enable cleavage or inhibition of desired transcripts, have significant off-target effects and remain challenging engineering targets due to their key role in endogenous processes (Birmingham et al., 2006; Jackson et al., 2003).”
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. (2007, background): “However, many conclusions regarding base-pairing have been drawn from overexpression of miRNAs, in which nonphysiologic miRNA:mRNA interactions may occur and siRNA-like off-target effects may be observed (Birmingham et al., 2006; Jackson et al., 2006).”
Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing (2010, background): “In order to systematically analyze these sites, we therefore compiled additional array data from HeLa experiments with similarly transfected miRNAs and siRNAs (Birmingham et al., 2006; Jackson et al., 2006a, 2006b; Schwarz et al., 2006; Anderson et al., 2008).”