Microfluidic Large-Scale Integration
By Todd Thorsen, S. Maerkl, Stephen R. Quake. Science, 2002
1,295 citations recorded by the source corpus.
Subfields: Biomedical Engineering, Electrical and Electronic Engineering
View Paper: https://www.semanticscholar.org/paper/2664dd12b8e96f27f9266e4d40eca23291fff19c
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Biomedical Engineering
- Stephen R. Quake
- Demetri Psaltis
- J. Melin
- Zhenyu Li
- A. Ajdari
- Roland Zengerle
- S. Haeberle
- Petra S. Dittrich
In Electrical and Electronic Engineering
- Demetri Psaltis
- Zhenyu Li
- Stephen R. Quake
- J. Melin
- David A. Weitz
- Jie Xu
- Roland Zengerle
- S. Haeberle
Citations in the corpus
- ENGINEERING FLOWS IN SMALL DEVICES (2004, background): “In many applications a valuable feature of microflows is that the dynamics in a single channel can be replicated in many channels, which can be organized into subnetworks and controlled as indicated in Figure 1b (e.g., Thorsen et al. 2002).”
- Microfluidic large-scale integration: the evolution of design rules for biological automation. (2007, methodology): “This technology enables hundreds of assays to be performed in parallel with multiple reagents in an automated manner and has been used in applications such as protein crystallography (12–14), genetic analysis (26), amino acid analysis (36), high-throughput screening (42), bioreactors (10), chemical ”
- Advances in Microfluidic PCR for Point-of-Care Infectious Disease Diagnostics (2011, background): “Recently, polymeric materials such as polydimethylsiloxane (PDMS) (Thorsen et al. , 2002, Unger et al. , 2000), polymethylmethacrylate (PMMA) (Hataoka et al. , 2004, Lee et al. , 2004), and polycarbonate (PC) (Hashimoto et al. , 2004, Liu et al. , 2002) have become more popular owing primarily to…”
- Xurography: rapid prototyping of microstructures using a cutting plotter (2005, methodology): “Current commercial rapid prototyping methods for microstructures include: micromolding in polydimethylsiloxane (PDMS) [2]–[9], laser ablation [10]–[14], stereo lithography [15], micropowder blasting [10], hot embossing [4], [16], and micromilling [17].”
- Droplet-based microfluidic platforms for the encapsulation and screening of Mammalian cells and multicellular organisms. (2008, background): “It has even enabled sophisticated microfluidic arrays containing thousands of compartments separated by valves (Thorsen et al., 2002).”
- Optofluidic dye lasers (2008, positive): “Highly automated microfluidic manipulation and large-scale integration also became possible after the development of soft elastomer-based on-chip mechanical valves and pumps (Unger et al. 2000; Thorsen et al. 2002; Hong and Quake 2003).”
- Multiplexed Point-of-Care Testing – xPOCT (2017, methodology): “introduced an analogy to VLSI technology, microfluidic large-scale integration (mLSI), in 2002 [63].”