Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner
By S. Galloway, K. McNatty, Lisa M. Cambridge, Mika P. E. Laitinen, J. Juengel, S. Jokiranta, R. J. McLaren, K. Luiro, Ken G. Dodds, Grant W. Montgomery and 3 more. Nature Genetics, 2000
1,129 citations recorded by the source corpus.
Subfields: Molecular Biology, Pediatrics, Perinatology and Child Health, Public Health, Environmental and Occupational Health
View Paper: https://www.semanticscholar.org/paper/25ba2ae89e3f8067bac472912dca60d8519d9faa
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Citations in the corpus
- Oocyte control of ovarian follicular development and function in mammals. (2001, background): “Thus, synergism between Gdf9 and Bmp15 is required for normal follicular and oocyte development in mice.”
- Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function. (2001, background): “The BMP15 gene was cloned in sheep and shown to be mutated in Inverdale and Hanna sheep carrying the fecundity X (FecX and FecX) mutations (21).”
- The mammalian ovary from genesis to revelation. (2009, background): “Linkage analysis, however, mapped the FecX allele to the BMP15 gene locus (234), which is in an orthologous location on mouse and human X chromosomes (229).”
- A method for meta‐analysis of molecular association studies (2005, background): “inverdale fecundity gene (where += + =1 lamb, += −=2 lambs, and −= −= infertile (overdriven streak ovaries)), however it is likely to be quite rare [53].”