Conditional modulation of spike-timing-dependent plasticity for olfactory learning

By S. Cassenaer, Gilles Laurent. 2012

232 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Ecology, Evolution, Behavior and Systematics, Genetics

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Citations in the corpus

Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila (2014, background): “In contrast to KCs, MBONs have broadly tuned odor responses; any given odor results in a response in most MBONs, although the magnitude of the response varies among MBON cell types (Hige et al., unpublished) (Cassenaer and Laurent, 2012).”
The neuronal architecture of the mushroom body provides a logic for associative learning (2014, background): “…the KCs of the MB comprise 2000 neurons that define only seven distinct cell types, receive unstructured, rather than stereotyped, inputs (Murthy et al., 2008; Caron et al., 2013; Gruntman and Turner, 2013), and connect to multiple MBONs through plastic synapses (Cassenaer and Laurent, 2007, 2012).”
Heterosynaptic plasticity underlies aversive olfactory learning in Drosophila (2015, unknown): “In other insects, it has been shown that electrical stimulation paradigms can induce plasticity at MB output in locusts (Cassenaer and Laurent, 2007; 2012) and bees (Oleskevich et al., 1997), where learning-related changes have also been seen (Mauelshagen, 1993; Okada et al., 2007; Strube-Bloss et…”
Oscillatory integration windows in neurons (2016, background): “The sparse responses of KCs may facilitate association of odors with reward (Laurent, 2002; Cassenaer and Laurent, 2012), consistent with a role for the mushroom bodies in olfactory learning (Keene and Waddell, 2007).”
Functional analysis of a higher olfactory center, the lateral horn (2012, background): “Recent work shows -LNs with somata near those of the LHIs (Cassenaer and Laurent, 2007) are inhibitory (Cassenaer and Laurent, 2012), suggesting the GABAergic cluster may also contain these -LNs.”
Sleep prevents catastrophic forgetting in spiking neural networks by forming a joint synaptic weight representation (2022, background): “In insects, Kenyon cells make plastic (subject to rewarded STDP) projections to the lobes [27,63].”
Pain-relief learning in flies, rats, and man: basic research and applied perspectives (2014, background): “We note, however, that the STDP rule is sensitive to neuromodulatory effects, as shown for the locust Kenyon cell output synapses (Cassenaer and Laurent 2012), and incorporating”
Feed-Forward versus Feedback Inhibition in a Basic Olfactory Circuit (2015, background): “FB inhibition exists in the MB of fly, cockroach, locust, honeybee, and mammal [13, 14, 16, 17].”
Neuromodulated Spike-Timing-Dependent Plasticity, and Theory of Three-Factor Learning Rules (2016, methodology): “In the drosophila mushroom body, the neuromodulator octopamine (thought to be functionally similar to noradrenaline) changes the STDP window from its “classic” shape to LTD for both timing orders (Cassenaer and Laurent, 2012).”
Activity of Defined Mushroom Body Output Neurons Underlies Learned Olfactory Behavior in Drosophila (2015, background): “, 2007) and locusts (Cassenaer and Laurent, 2012), although the importance of these synaptic connections in the behavior of these insects is not known.”