Epigenetic programming by maternal behavior

By I. Weaver, N. Cervoni, F. Champagne, A. D’Alessio, Shakti Sharma, J. Seckl, Sergiy Dymov, M. Szyf, Michael Joseph Meaney. Nature Neuroscience, 2004

5,920 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Molecular Biology, Social Psychology

View Paper: https://www.semanticscholar.org/paper/253b474a2f28469400f57c5b8ffca64aaf4122cc

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

1. Bruce S. McEwen
2. E. Nestler
3. Michael Joseph Meaney
4. Christine Marcelle Heim
5. C. Nemeroff
6. Gregory E. Miller
7. J. Seckl
8. M. Enoch

In Molecular Biology

1. Michael Joseph Meaney
2. E. Nestler
3. C. Alberini
4. G. Koob
5. Bruce S. McEwen
6. Christoph Bock
7. J. Seckl
8. Eva Jablonka

In Social Psychology

1. Michael Joseph Meaney
2. E. Nestler
3. Ruth Feldman
4. J. Seckl
5. Christine Marcelle Heim
6. Bruce S. McEwen
7. M. Enoch
8. Shelley E. Taylor

Citations in the corpus

• Fetal programming of hypothalamo‐pituitary‐adrenal function: prenatal stress and glucocorticoids (2006, background): “This effect is mediated via serotonin (5-HT7) receptors and appears to be permanent involving altered methylation of the GR promoter (Meaney et al. 2000; Weaver et al. 2004).”
• Addiction and the brain antireward system. (2008, background): “F or p er so na l u se o nl y. ANRV331-PS59-02 ARI 1 December 2007 15:57 Allostasis: stability through change gene expression changes (Lemaire et al. 2006, Meaney 2001, Vallée et al. 1999, Weaver et al. 2004).”
• Inherited epigenetic variation — revisiting soft inheritance (2006, background): “Another intriguing example of an environmentally induced, mitotically stable epiallele was recently described in rats: nurturing maternal behaviour leads to postnatal remodelling of the epigenetic state of the hippocampal glucocorticoid receptor gene ( GR ; also known as nuclear receptor subfamily 3”
• Maternal Genistein Alters Coat Color and Protects Avy Mouse Offspring from Obesity by Modifying the Fetal Epigenome (2006, background): “Genistein, the major isoflavone in soy, exhibits mixed estrogen agonist and antagonist properties (Price and Fenwick 1985), inhibits tyrosine kinase (Akiyama et al. 1987), and scavenges free radicals (Wei et al. 1993), depending on timing, dose, and the tissue examined.”
• Antenatal maternal stress and long-term effects on child neurodevelopment: how and why? (2007, background): “Recently, this group (Weaver et al., 2004) has shown that this increased nurturing is associated with less methylation of the promoter region of the GR gene in the hippocampus.”