Chronic neuropathologies of single and repetitive TBI: substrates of dementia?

By Douglas H. Smith, Victoria E. Johnson, W. Stewart. Nature Reviews Neurology, 2013

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Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury (2014, background): “Moderate to severe traumatic brain injury (TBI) is an established risk factor for the development of neurodegeneration, including AD, with a single episode of TBI conferring an increased risk of dementia later in life (Guo et al., 2000; Plassman et al., 2000; Moretti et al., 2012; D.H. Smith et al.,”
The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy (2015, background): “1 3 described following exposure to single moderate or severe traumatic brain injury, together with Aβ plaques [20, 44].”
Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population‐based perspective (2015, neutral): “[118] Smith DH, Johnson VE, Stewart W.”