Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu.

By K. Nakanishi, T. Yoshimoto, H. Tsutsui, H. Okamura. Cytokine & growth factor reviews, 2001

684 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/2522a1fb2a85227d9a6ca71dc6f36919838f9932

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. J. Tschopp
2. Annick Mayor
3. Fabio Martinon
4. Shizuo Akira
5. T. Kanneganti
6. Kate Schroder
7. Satoshi Uematsu
8. O. Takeuchi

In Molecular Biology

1. J. Tschopp
2. Fabio Martinon
3. Annick Mayor
4. Kate Schroder
5. G. Núñez
6. Shizuo Akira
7. T. Kanneganti
8. M. Lamkanfi

Citations in the corpus

• The inflammasomes: guardians of the body. (2009, background): “IL-18, which is commonly considered to promote Th1 immunity, can amplify Th2 responses and promote Th2-biased pathologies, such as asthma, by triggering the production of IgE antibodies (234).”